What Is The Main Causes of Anaemia

Blood Loss

Blood loss is the common cause of anaemia, especially iron-deficiency anaemia. Blood loss can be short-term or persist over time. Heavy menstrual periods or bleeding in the digestive or urinary tract can cause blood loss. Surgery, trauma, or cancer also can cause blood loss. If a lot of blood is lost, the body may lose enough red blood cells to cause anaemia.


Lack of Red Blood Cell Production

Both acquired and
inherited conditions and factors can prevent your body from making enough red blood cells. Acquired means you are not born with the condition, but you develop it. Inherited means your parents passed the gene for the condition on to you. Acquired conditions and factors that can lead to anaemia include a poor diet, abnormal hormone levels, some chronic (ongoing) diseases, and pregnancy.



A diet that lacks iron, folic acid (folate), or vitamin B12 can prevent your body from making enough red blood cells. Your body also needs a small amount of vitamin C, riboflavin, and copper to make red blood cells. Conditions that make it hard for your body to absorb nutrients also can prevent your body from making enough red blood cells.

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Your body needs the hormone erythropoietin (eh-rith-POY-eh -tin) to make red blood cells. This hormone stimulates the bone marrow to make these cells. A low level of this cell's hormone can lead to anaemia.


Diseases and Disease Treatments

Chronic diseases, like kidney disease and cancer, can make it hard for your body to make enough red blood cells. Some cancer treatments may damage the bone marrow or damage the red blood cells' ability to carry oxygen. If the bone marrow is damaged, it cannot make red blood cells fast enough to replace the ones that die or are destroyed. People who have HIV/AIDS may develop anaemia due to infections or medicines used to treat their diseases.



 Anaemia can occur during pregnancy due to a low level of iron and folic acid and changes in the blood. During the first 6 months of pregnancy, the fluid portion of woman blood (the plasma) increases faster than the red blood cells. This dilutes the blood and can lead to anaemia.


Aplastic Anaemia

Some infants are born without the ability to make enough red blood cells. This condition is called aplastic anaemia. Infants and children who have aplastic anaemia often need blood transfusions to increase the number of red blood cells in their blood. Acquired conditions or factors, such as certain medicines, toxins, and infectious diseases, also can cause aplastic anaemia.

High Rates of Red Blood Cell 

Destruction both acquired and inherited conditions and factors can cause your body to destroy too many red blood cells. One example of an acquired condition is an enlarged or diseased spleen. The spleen is an organ that removes worn-out red blood cells from the body. If the spleen is enlarged or diseased, it may remove more red blood cells than normal, causing anaemia.

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